Rattlesnake Creek begins near Tooley Corners in Spring Brook Township. It flows south for a few tenths of a mile and enters Maple Lake. On the southern side of the lake, it flows south for several tenths of a mile, crossing Pennsylvania Route 690 and receiving the tributary Six Springs Creek from the. The creek then turns west for more than a mile before turning northwest and then north-northwest. After a few miles, it turns southwest and reaches its confluence with Spring Brook in the Nesbitt Reservoir. Rattlesnake Creek joins Spring Brook upstream of its mouth.
Tributaries
Rattlesnake Creek has one named tributary, which is known as Six Springs Creek. Six Springs Creek joins Rattlesnake Creek upstream of its mouth. Its watershed has an area of.
Hydrology
The concentration of alkalinity in Rattlesnake Creek is 17 milligrams per liter.
Geography and geology
The elevation near the mouth of Rattlesnake Creek is above sea level. The elevation near the source of the creek is between above sea level. The surficial geology along Rattlesnake Creek near its mouth mainly consists of alluvium. However, some patches of Wisconsinan Ice-Contact Stratified Drift and alluvial fan are present, as are larger areas of a glacial or resedimented till known as Wisconsinan Till and bedrock consisting ofconglomerate, sandstone, and shale. Further upstream, the surficial geology immediately adjacent to the creek consists of alluvium, but it eventually switches to Wisconsinan Till, which also makes up most of the surficial geology elsewhere in the watershed. However, there are a few large patches of bedrock and a few small patches of Wisconsinan Ice-Contact Stratified Drift. Additionally, there are several patches of wetlands and peat bogs, especially near the headwaters.
Watershed
The watershed of Rattlesnake Creek has an area of. The mouth of the creek is in the United States Geological Survey quadrangle of Avoca. However, its source is in the quadrangle of Moscow. A lake known as Maple Lake is on the upper reaches of Rattlesnake Creek. It has an area of approximately. The lake is dammed by the Maple Lake Dam, a homogeneous earthfill embankment. The dam has a width of and a maximum height of. Below the second Pennsylvania Route 690 crossing, Rattlesnake Creek is entirely on private land and is closed to access.
Wild trout naturally reproduce in Rattlesnake Creek from its headwaters downstream to its mouth. The creek is also considered by the Pennsylvania Fish and Boat Commission to be Class A Wild Trout Waters for brook trout and brown trout from the second crossing of Pennsylvania Route 690 downstream to its mouth, a distance of. The creek has supported trout populations as early as the 1970s.